Diclazuril Protects against Maternal Gastrointestinal Syndrome and Congenital Toxoplasmosis
نویسندگان
چکیده
منابع مشابه
Diclazuril Protects against Maternal Gastrointestinal Syndrome and Congenital Toxoplasmosis
BACKGROUND Toxoplasmosis is a common cause of foodborne, gastrointestinal and congenital syndrome with particularly severe or unknown health consequences. There is no safe and effective preventive or therapeutic modality against congenital toxoplasmosis or to eliminate the persistent chronic infection. HYPOTHESIS Diclazuril to be safe in pregnancy and effective against gastrointestinal toxopl...
متن کاملNovel Synergistic Protective Efficacy of Atovaquone and Diclazuril on Fetal-Maternal Toxoplasmosis.
Over 1 billion people globally are estimated to be infected with Toxoplasma gondii with severe or unknown consequences and no safe and effective therapies are available against congenital or persistent chronic infection. We propose that atovaquone and diclazuril synergistically protect against fetal-maternal toxoplasmosis. METHODS Programmed pregnant mice were treated with atovaquone and dicl...
متن کاملCongenital toxoplasmosis.
Congenital toxoplasmosis results from the transplacental transmission of the parasite Toxoplasma gondii after a maternal infection acquired in pregnancy. Prevalence of congenital infection ranges from 0.1 to 0.3 per 1000 live births. The maternal-fetal transmission rate increases with gestational age at maternal seroconversion, from less than 15% at 13 weeks of gestation to over 70% at 36 weeks...
متن کاملCongenital toxoplasmosis.
The history of toxoplasmosis began in 1923 with the F first published description of a human case, a congenitally infected baby. Toxoplasma gondii had been recognised 15 years earlier, but it was not until 1%96 that the life cycle of this protozoan parasite was understood, with the discovery that the definitive host : was any member of the cat family (fig 1).' 2 _ Despite extensive clinical and...
متن کامل[Congenital toxoplasmosis].
Since congenital toxoplasmosis was first recognized as a human infection 18 years ago, it has been found in many parts of the world, and, following the first report by Jacoby and Sagorin in 1948, over 50 cases have been recorded in the British literature. Only four of the reports from this country concern the findings in fatal cases (Cathie and Dudgeon, 1949; Valentine, 1952; Valentine, Lane, B...
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ژورنال
عنوان ژورنال: International Journal of Clinical Medicine
سال: 2014
ISSN: 2158-284X,2158-2882
DOI: 10.4236/ijcm.2014.53017